Publications

PDF   Taylor, L., Chaudhary, G., Jain, G., Lowe, A., Hupe, A., Negishi, A., … & Fudge, D. S. (2023). Mechanisms of gill-clogging by hagfish slime. Journal of the Royal Society Interface, 20(200), 20220774.

PDF     Zeng Y., Petrichko S, Nieders K., Plachetzki D, and Fudge D.S. (2021) Evolution of a remarkable intracellular polymer and extreme cell allometry in hagfishes. Current Biology, 31: 5062-8.

PDF      Bressman, N., & Fudge, D.S. (2021). From reductionionism to synthesis: the case of hagfish slime. Comparative Biochemistry and Physiology, Part B, 255, 1-10.

PDF     Mincarone, M. M., Plachetzki, D., McCord, C.L., Winegard, T.M., Fernholm, B, Gonzalez, C.J., & Fudge, D.S. (2021). Review of the hagfishes (Myxinidae) from the Galapagos Islands, with descriptions of four new species and their phylogenetic relationships. Zoological Journal of the Linnean Society, 192, 453-474.

PDF     McCord, C., Whiteley, E., Liang, J., Trejo, C., Caputo, R., Itehua, E., Hasan, H., Hernandez, S., Jagnandan, K., & Fudge, D. S. (2020). Concentration effects of three common fish anesthetics on Pacific hagfish (Eptatretus stoutii). Fish Physiol Biochem, 46, 931-944.

PDF     Fudge, D. S., Ferraro, F.N., Siwiecki, S.A., Hupe, A., & Jain, G. (2020). A new model of hagfish slime mucous vesicle stabilization and deployment. Langmuir, 36(24), 6681-6689.

PDF     Black, K.L., Fudge, D. S., Jarvis, W.M.C., & Robinson, B.W. (2019). Functional plasticity in lamellar autotomy by larval damselflies in response to predatory larval dragonfly cues. Evolutionary Ecology, 33, 257-272.

PDF     Jain, G., Starksen, M., Singh, K., Hoang, C., Yancey, P., McCord, C., & Fudge, D. S. (2019). High concentrations of trimethylamines in slime glands inhibit skein unraveling in Pacific Hagfish. Journal of Experimental Biology , 222(22).

PDF   Bernards Jr., M. A., Schorno, S., McKenzie, E., Winegard, T. M., Oke, I., Plachetzki, D. & Fudge, D. S. (2018). Unraveling inter-species differences in hagfish slime skein deploymentJournal of Experimental Biology, 221, 1-11.

PDF   Schorno, S., Gillis, T. E. & Fudge, D. S. (2018). Cellular mechanisms of slime gland refilling in Pacific hagfish (Eptatretus stoutii). Journal of Experimental Biology, 221, 1-11.

PDF   Schorno, S., Gillis, T. E. & Fudge, D. S. (2018). Emptying and refilling of slime glands in Atlantic (Myxine glutinosa) and Pacific (Eptatretus stoutii) hagfishes. Journal of Experimental Biology, 221, 1-8.

PDF     Freedman, C.  R. & Fudge, D. S. (2017). Hagfish houdinis: biomechanics and behavior of squeezing through small openings. Journal of Experimental Biology, 220, 822-827.

PDF     Boggett, S., Stiles, J-L, Summers, A. P. & Fudge, D. S. (2017). Flaccid skin protects hagfishes from shark bites. J. R. Soc.
Interface, 14: 20170765.

PDF     Weatherbee-Martin, N., Xu, L., Hupe, A., Kreplak, L., Fudge, D. S., Liu, X., & Rainey, J. K. (2016). Identification of wet-spinning and post-spin stretching methods amenable to recombinant spider aciniform silk. Biomacromolecules, 17(8), 2737-2746.

PDF     Icardo, J. M., Colvee, E., Schorno, S., Lauriano, E. R., Fudge, D. S., Glover, C. N., & Zaccone, G. (2016). Morphological analysis of the hagfish heart. II. The venous pole and the pericardium. Journal of Morphology, 277(7), 853-865.

PDF     Fudge, D. S., & Schorno, S. (2016). The hagfish gland thread cell: a fiber-producing cell involved in predator defense.  Cells, 5(2), 25.

PDF     Fudge, D. S., Schorno, S., & Ferraro, S. (2014). Physiology, biomechanics, and biomimetics of hagfish slime. Annual Review of Biochemistry, (0).

PDF     Won, G. J., Fudge, D. S., & Choh, V. (2015). The effects of actomyosin disruptors on the mechanical integrity of the avian crystalline lens. Molecular vision21, 98.

PDF     Winegard, T., Herr, J., Mena, C., Lee, B., Dinov, I., Bird, D., … & Fudge, D. (2014). Coiling and maturation of a high-performance fibre in hagfish slime gland thread cells. Nature communications5.

PDF     Pinto, N., Yang, F. C., Negishi, A., Rheinstädter, M. C., Gillis, T. E., & Fudge, D. S. (2014). Self-assembly enhances the strength of fibers made from vimentin intermediate filament proteins. Biomacromolecules15(2), 574-581.

PDF    Bernards, M. A., Oke, I., Heyland, A., & Fudge, D. S. (2014). Spontaneous unraveling of hagfish slime thread skeins is mediated by a seawater-soluble protein adhesive. The Journal of experimental biology217(8), 1263-1268.

PDF     Fudge, D. S. (2014). Fifty years of JR Platt’s strong inference. The Journal of experimental biology217(8), 1202-1204.

PDF     Herr, J. E., Clifford, A., Goss, G. G., & Fudge, D. S. (2014). Defensive slime formation in Pacific hagfish requires Ca2+ and aquaporin mediated swelling of released mucin vesicles. The Journal of experimental biology, 217: 2288-2296

PDF     Gleason, J. E., Fudge, D. S., & Robinson, B. W. (2014). Eco-mechanics of lamellar autotomy in larval damselflies. The Journal of experimental biology, 217(2), 185-191.

PDF     Negishi, A., Armstrong, C. L., Kreplak, L., Rheinstadter, M. C., Lim, L. T., Gillis, T. E., & Fudge, D. S. (2012). The production of fibers and films from solubilized hagfish slime thread proteins. Biomacromolecules13(11), 3475-3482.

PDF     Greenberg, D. A., & Fudge, D. S. (2013). Regulation of hard α-keratin mechanics via control of intermediate filament hydration: matrix squeeze revisited. Proceedings of the Royal Society B: Biological Sciences280(1750), 20122158.

PDF     Beriault, D. R., Haddad, O., McCuaig, J. V., Robinson, Z. J., Russell, D., Lane, E. B., & Fudge, D. S. (2012). The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes. PloS one7(2), e31320.

PDF     Fudge, D. S., McCuaig, J. V., Van Stralen, S., Hess, J. F., Wang, H., Mathias, R. T., & FitzGerald, P. G. (2011). Intermediate filaments regulate tissue size and stiffness in the murine lens. Investigative ophthalmology & visual science, 52(6), 3860-3867.

PDF    Ewoldt, R. H., Winegard, T. M., & Fudge, D. S. (2011). Non-linear viscoelasticity of hagfish slime. International Journal of Non-Linear Mechanics, 46(4), 627-636.

PDF     Fudge, D. S., Hillis, S., Levy, N., & Gosline, J. M. (2010). Hagfish slime threads as a biomimetic model for high performance protein fibres. Bioinspiration & biomimetics5(3), 035002.

PDF     Szewciw, L. J., De Kerckhove, D. G., Grime, G. W., & Fudge, D. S. (2010). Calcification provides mechanical reinforcement to whale baleen α-keratin. Proceedings of the Royal Society B: Biological Sciences, 277(1694), 2597-2605, rspb20100399.

PDF     Herr, J. E., Winegard, T. M., O’Donnell, M. J., Yancey, P. H., & Fudge, D. S. (2010). Stabilization and swelling of hagfish slime mucin vesicles. The Journal of experimental biology213(7), 1092-1099.

PDF     Winegard, T. M., & Fudge, D. S. (2010). Deployment of hagfish slime thread skeins requires the transmission of mixing forces via mucin strands. The Journal of Experimental Biology213(8), 1235-1240.

PDF     LeBlanc, D. M., Wood, C. M., Fudge, D. S., & Wright, P. A. (2010). A fish out of water: gill and skin remodeling promotes osmo-and ionoregulation in the mangrove killifish Kryptolebias marmoratus. Physiological and Biochemical Zoology83(6), 932-949.

PDF    Fudge, D.S., Winegard, T., Ewoldt, R.H. Beriault, D., Szewciw, L., and McKinley, G.H. (2009) From ultra-soft slime to hard alpha-keratins: the many lives of intermediate filaments. Integrative and Comparative Biology, 49(1), 32-39.

PDF     Fudge, D. S., Szewciw, L. J., & Schwalb, A. N. (2009). Morphology and development of blue whale baleen: an annotated translation of Tycho Tullberg’s classic 1883 paper. Aquatic Mammals35(2), 226.

PDF    Fudge, D., Russell, D., Beriault, D., Moore, W., Lane, E. B., & Vogl, A. W. (2008). The intermediate filament network in cultured human keratinocytes is remarkably extensible and resilient. PLoS One3(6), e2327.

PDF     Kreplak, L., & Fudge, D. (2007). Biomechanical properties of intermediate filaments: from tissues to single filaments and back. Bioessays29(1), 26-35.

PDF     Lim, J., Fudge, D. S., Levy, N., & Gosline, J. M. (2006). Hagfish slime ecomechanics: testing the gill-clogging hypothesis. Journal of experimental biology209(4), 702-710.

PDF     John M. Gosline, Douglas S. Fudge, and Paul A. Guerette. (2006). Alpha-helical protein based materials and methods for making same (patent).

PDF     Fudge, D. S., Levy, N., Chiu, S., & Gosline, J. M. (2005). Composition, morphology and mechanics of hagfish slime. Journal of experimental biology,208(24), 4613-4625.

PDF     Fudge, D. S., & Gosline, J. M. (2004). Molecular design of the α–keratin composite: insights from a matrix–free model, hagfish slime threads. Proceedings of the Royal Society of London. Series B: Biological Sciences,271(1536), 291-299.

PDF    Fudge, D. S., Gardner, K. H., Forsyth, V. T., Riekel, C., & Gosline, J. M. (2003). The mechanical properties of hydrated intermediate filaments: insights from hagfish slime threads. Biophysical Journal85(3), 2015-2027.