Publications

PDF   Zeng, Y., Plachetzki, D.C., Nieders, K., Campbell, H., Cartee, M., Pankey, M.S., Guillen, K. and Fudge, D., (2023). Epidermal threads reveal the origin of hagfish slime. Elife, 12, p.e81405.

PDF   Taylor, L., Chaudhary, G., Jain, G., Lowe, A., Hupe, A., Negishi, A., … & Fudge, D. S. (2023). Mechanisms of gill-clogging by hagfish slime. Journal of the Royal Society Interface, 20(200), 20220774.

PDF     Zeng Y., Petrichko S, Nieders K., Plachetzki D, and Fudge D.S. (2021) Evolution of a remarkable intracellular polymer and extreme cell allometry in hagfishes. Current Biology, 31: 5062-8.

PDF      Bressman, N., & Fudge, D.S. (2021). From reductionionism to synthesis: the case of hagfish slime. Comparative Biochemistry and Physiology, Part B, 255, 1-10.

PDF     Mincarone, M. M., Plachetzki, D., McCord, C.L., Winegard, T.M., Fernholm, B, Gonzalez, C.J., & Fudge, D.S. (2021). Review of the hagfishes (Myxinidae) from the Galapagos Islands, with descriptions of four new species and their phylogenetic relationships. Zoological Journal of the Linnean Society, 192, 453-474.

PDF     McCord, C., Whiteley, E., Liang, J., Trejo, C., Caputo, R., Itehua, E., Hasan, H., Hernandez, S., Jagnandan, K., & Fudge, D. S. (2020). Concentration effects of three common fish anesthetics on Pacific hagfish (Eptatretus stoutii). Fish Physiol Biochem, 46, 931-944.

PDF     Fudge, D. S., Ferraro, F.N., Siwiecki, S.A., Hupe, A., & Jain, G. (2020). A new model of hagfish slime mucous vesicle stabilization and deployment. Langmuir, 36(24), 6681-6689.

PDF     Black, K.L., Fudge, D. S., Jarvis, W.M.C., & Robinson, B.W. (2019). Functional plasticity in lamellar autotomy by larval damselflies in response to predatory larval dragonfly cues. Evolutionary Ecology, 33, 257-272.

PDF     Jain, G., Starksen, M., Singh, K., Hoang, C., Yancey, P., McCord, C., & Fudge, D. S. (2019). High concentrations of trimethylamines in slime glands inhibit skein unraveling in Pacific Hagfish. Journal of Experimental Biology , 222(22).

PDF   Bernards Jr., M. A., Schorno, S., McKenzie, E., Winegard, T. M., Oke, I., Plachetzki, D. & Fudge, D. S. (2018). Unraveling inter-species differences in hagfish slime skein deploymentJournal of Experimental Biology, 221, 1-11.

PDF   Schorno, S., Gillis, T. E. & Fudge, D. S. (2018). Cellular mechanisms of slime gland refilling in Pacific hagfish (Eptatretus stoutii). Journal of Experimental Biology, 221, 1-11.

PDF   Schorno, S., Gillis, T. E. & Fudge, D. S. (2018). Emptying and refilling of slime glands in Atlantic (Myxine glutinosa) and Pacific (Eptatretus stoutii) hagfishes. Journal of Experimental Biology, 221, 1-8.

PDF     Freedman, C.  R. & Fudge, D. S. (2017). Hagfish houdinis: biomechanics and behavior of squeezing through small openings. Journal of Experimental Biology, 220, 822-827.

PDF     Boggett, S., Stiles, J-L, Summers, A. P. & Fudge, D. S. (2017). Flaccid skin protects hagfishes from shark bites. J. R. Soc.
Interface, 14: 20170765.

PDF     Weatherbee-Martin, N., Xu, L., Hupe, A., Kreplak, L., Fudge, D. S., Liu, X., & Rainey, J. K. (2016). Identification of wet-spinning and post-spin stretching methods amenable to recombinant spider aciniform silk. Biomacromolecules, 17(8), 2737-2746.

PDF     Icardo, J. M., Colvee, E., Schorno, S., Lauriano, E. R., Fudge, D. S., Glover, C. N., & Zaccone, G. (2016). Morphological analysis of the hagfish heart. II. The venous pole and the pericardium. Journal of Morphology, 277(7), 853-865.

PDF     Fudge, D. S., & Schorno, S. (2016). The hagfish gland thread cell: a fiber-producing cell involved in predator defense.  Cells, 5(2), 25.

PDF     Fudge, D. S., Schorno, S., & Ferraro, S. (2014). Physiology, biomechanics, and biomimetics of hagfish slime. Annual Review of Biochemistry, (0).

PDF     Won, G. J., Fudge, D. S., & Choh, V. (2015). The effects of actomyosin disruptors on the mechanical integrity of the avian crystalline lens. Molecular vision21, 98.

PDF     Winegard, T., Herr, J., Mena, C., Lee, B., Dinov, I., Bird, D., … & Fudge, D. (2014). Coiling and maturation of a high-performance fibre in hagfish slime gland thread cells. Nature communications5.

PDF     Pinto, N., Yang, F. C., Negishi, A., Rheinstädter, M. C., Gillis, T. E., & Fudge, D. S. (2014). Self-assembly enhances the strength of fibers made from vimentin intermediate filament proteins. Biomacromolecules15(2), 574-581.

PDF    Bernards, M. A., Oke, I., Heyland, A., & Fudge, D. S. (2014). Spontaneous unraveling of hagfish slime thread skeins is mediated by a seawater-soluble protein adhesive. The Journal of experimental biology217(8), 1263-1268.

PDF     Fudge, D. S. (2014). Fifty years of JR Platt’s strong inference. The Journal of experimental biology217(8), 1202-1204.

PDF     Herr, J. E., Clifford, A., Goss, G. G., & Fudge, D. S. (2014). Defensive slime formation in Pacific hagfish requires Ca2+ and aquaporin mediated swelling of released mucin vesicles. The Journal of experimental biology, 217: 2288-2296

PDF     Gleason, J. E., Fudge, D. S., & Robinson, B. W. (2014). Eco-mechanics of lamellar autotomy in larval damselflies. The Journal of experimental biology, 217(2), 185-191.

PDF     Negishi, A., Armstrong, C. L., Kreplak, L., Rheinstadter, M. C., Lim, L. T., Gillis, T. E., & Fudge, D. S. (2012). The production of fibers and films from solubilized hagfish slime thread proteins. Biomacromolecules13(11), 3475-3482.

PDF     Greenberg, D. A., & Fudge, D. S. (2013). Regulation of hard α-keratin mechanics via control of intermediate filament hydration: matrix squeeze revisited. Proceedings of the Royal Society B: Biological Sciences280(1750), 20122158.

PDF     Beriault, D. R., Haddad, O., McCuaig, J. V., Robinson, Z. J., Russell, D., Lane, E. B., & Fudge, D. S. (2012). The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes. PloS one7(2), e31320.

PDF     Fudge, D. S., McCuaig, J. V., Van Stralen, S., Hess, J. F., Wang, H., Mathias, R. T., & FitzGerald, P. G. (2011). Intermediate filaments regulate tissue size and stiffness in the murine lens. Investigative ophthalmology & visual science, 52(6), 3860-3867.

PDF    Ewoldt, R. H., Winegard, T. M., & Fudge, D. S. (2011). Non-linear viscoelasticity of hagfish slime. International Journal of Non-Linear Mechanics, 46(4), 627-636.

PDF     Fudge, D. S., Hillis, S., Levy, N., & Gosline, J. M. (2010). Hagfish slime threads as a biomimetic model for high performance protein fibres. Bioinspiration & biomimetics5(3), 035002.

PDF     Szewciw, L. J., De Kerckhove, D. G., Grime, G. W., & Fudge, D. S. (2010). Calcification provides mechanical reinforcement to whale baleen α-keratin. Proceedings of the Royal Society B: Biological Sciences, 277(1694), 2597-2605, rspb20100399.

PDF     Herr, J. E., Winegard, T. M., O’Donnell, M. J., Yancey, P. H., & Fudge, D. S. (2010). Stabilization and swelling of hagfish slime mucin vesicles. The Journal of experimental biology213(7), 1092-1099.

PDF     Winegard, T. M., & Fudge, D. S. (2010). Deployment of hagfish slime thread skeins requires the transmission of mixing forces via mucin strands. The Journal of Experimental Biology213(8), 1235-1240.

PDF     LeBlanc, D. M., Wood, C. M., Fudge, D. S., & Wright, P. A. (2010). A fish out of water: gill and skin remodeling promotes osmo-and ionoregulation in the mangrove killifish Kryptolebias marmoratus. Physiological and Biochemical Zoology83(6), 932-949.

PDF    Fudge, D.S., Winegard, T., Ewoldt, R.H. Beriault, D., Szewciw, L., and McKinley, G.H. (2009) From ultra-soft slime to hard alpha-keratins: the many lives of intermediate filaments. Integrative and Comparative Biology, 49(1), 32-39.

PDF     Fudge, D. S., Szewciw, L. J., & Schwalb, A. N. (2009). Morphology and development of blue whale baleen: an annotated translation of Tycho Tullberg’s classic 1883 paper. Aquatic Mammals35(2), 226.

PDF    Fudge, D., Russell, D., Beriault, D., Moore, W., Lane, E. B., & Vogl, A. W. (2008). The intermediate filament network in cultured human keratinocytes is remarkably extensible and resilient. PLoS One3(6), e2327.

PDF     Kreplak, L., & Fudge, D. (2007). Biomechanical properties of intermediate filaments: from tissues to single filaments and back. Bioessays29(1), 26-35.

PDF     Lim, J., Fudge, D. S., Levy, N., & Gosline, J. M. (2006). Hagfish slime ecomechanics: testing the gill-clogging hypothesis. Journal of experimental biology209(4), 702-710.

PDF     John M. Gosline, Douglas S. Fudge, and Paul A. Guerette. (2006). Alpha-helical protein based materials and methods for making same (patent).

PDF     Fudge, D. S., Levy, N., Chiu, S., & Gosline, J. M. (2005). Composition, morphology and mechanics of hagfish slime. Journal of experimental biology,208(24), 4613-4625.

PDF     Fudge, D. S., & Gosline, J. M. (2004). Molecular design of the α–keratin composite: insights from a matrix–free model, hagfish slime threads. Proceedings of the Royal Society of London. Series B: Biological Sciences,271(1536), 291-299.

PDF    Fudge, D. S., Gardner, K. H., Forsyth, V. T., Riekel, C., & Gosline, J. M. (2003). The mechanical properties of hydrated intermediate filaments: insights from hagfish slime threads. Biophysical Journal85(3), 2015-2027.