Publications
PDF Fudge, D.S., Lee, J., Guillen, K., Donatelli, C.M., Lowe, A., Arnold, L., Kahale-Lua, K., Quinteros, C., Ly, P., Atkins, L. and Bressman, N. (2024). Biphasic burrowing in Atlantic hagfish (Myxine limosa). Journal of Experimental Biology, 227(12), jeb247544.
PDF Zeng, Y., Plachetzki, D.C., Nieders, K., Campbell, H., Cartee, M., Pankey, M.S., Guillen, K. and Fudge, D., (2023). Epidermal threads reveal the origin of hagfish slime. Elife, 12, p.e81405.
PDF Taylor, L., Chaudhary, G., Jain, G., Lowe, A., Hupe, A., Negishi, A., Zeng, Y., Ewoldt, R.H. and Fudge, D.S.(2023). Mechanisms of gill-clogging by hagfish slime. Journal of the Royal Society Interface, 20(200), 20220774.
PDF Zeng Y., Petrichko S, Nieders K., Plachetzki D, and Fudge D.S. (2021) Evolution of a remarkable intracellular polymer and extreme cell allometry in hagfishes. Current Biology, 31: 5062-8.
PDF Bressman, N., & Fudge, D.S. (2021). From reductionionism to synthesis: the case of hagfish slime. Comparative Biochemistry and Physiology, Part B, 255, 1-10.
PDF Mincarone, M. M., Plachetzki, D., McCord, C.L., Winegard, T.M., Fernholm, B, Gonzalez, C.J., & Fudge, D.S. (2021). Review of the hagfishes (Myxinidae) from the Galapagos Islands, with descriptions of four new species and their phylogenetic relationships. Zoological Journal of the Linnean Society, 192, 453-474.
PDF McCord, C., Whiteley, E., Liang, J., Trejo, C., Caputo, R., Itehua, E., Hasan, H., Hernandez, S., Jagnandan, K., & Fudge, D. S. (2020). Concentration effects of three common fish anesthetics on Pacific hagfish (Eptatretus stoutii). Fish Physiol Biochem, 46, 931-944.
PDF Fudge, D. S., Ferraro, F.N., Siwiecki, S.A., Hupe, A., & Jain, G. (2020). A new model of hagfish slime mucous vesicle stabilization and deployment. Langmuir, 36(24), 6681-6689.
PDF Black, K.L., Fudge, D. S., Jarvis, W.M.C., & Robinson, B.W. (2019). Functional plasticity in lamellar autotomy by larval damselflies in response to predatory larval dragonfly cues. Evolutionary Ecology, 33, 257-272.
PDF Jain, G., Starksen, M., Singh, K., Hoang, C., Yancey, P., McCord, C., & Fudge, D. S. (2019). High concentrations of trimethylamines in slime glands inhibit skein unraveling in Pacific Hagfish. Journal of Experimental Biology , 222(22).
PDF Bernards Jr., M. A., Schorno, S., McKenzie, E., Winegard, T. M., Oke, I., Plachetzki, D. & Fudge, D. S. (2018). Unraveling inter-species differences in hagfish slime skein deployment. Journal of Experimental Biology, 221, 1-11.
PDF Schorno, S., Gillis, T. E. & Fudge, D. S. (2018). Cellular mechanisms of slime gland refilling in Pacific hagfish (Eptatretus stoutii). Journal of Experimental Biology, 221, 1-11.
PDF Schorno, S., Gillis, T. E. & Fudge, D. S. (2018). Emptying and refilling of slime glands in Atlantic (Myxine glutinosa) and Pacific (Eptatretus stoutii) hagfishes. Journal of Experimental Biology, 221, 1-8.
PDF Freedman, C. R. & Fudge, D. S. (2017). Hagfish houdinis: biomechanics and behavior of squeezing through small openings. Journal of Experimental Biology, 220, 822-827.
PDF Boggett, S., Stiles, J-L, Summers, A. P. & Fudge, D. S. (2017). Flaccid skin protects hagfishes from shark bites. J. R. Soc.
Interface, 14: 20170765.
PDF Weatherbee-Martin, N., Xu, L., Hupe, A., Kreplak, L., Fudge, D. S., Liu, X., & Rainey, J. K. (2016). Identification of wet-spinning and post-spin stretching methods amenable to recombinant spider aciniform silk. Biomacromolecules, 17(8), 2737-2746.
PDF Icardo, J. M., Colvee, E., Schorno, S., Lauriano, E. R., Fudge, D. S., Glover, C. N., & Zaccone, G. (2016). Morphological analysis of the hagfish heart. II. The venous pole and the pericardium. Journal of Morphology, 277(7), 853-865.
PDF Fudge, D. S., & Schorno, S. (2016). The hagfish gland thread cell: a fiber-producing cell involved in predator defense. Cells, 5(2), 25.
PDF Fudge, D. S., Schorno, S., & Ferraro, S. (2014). Physiology, biomechanics, and biomimetics of hagfish slime. Annual Review of Biochemistry, (0).
PDF Won, G. J., Fudge, D. S., & Choh, V. (2015). The effects of actomyosin disruptors on the mechanical integrity of the avian crystalline lens. Molecular vision, 21, 98.
PDF Winegard, T., Herr, J., Mena, C., Lee, B., Dinov, I., Bird, D., … & Fudge, D. (2014). Coiling and maturation of a high-performance fibre in hagfish slime gland thread cells. Nature communications, 5.
PDF Pinto, N., Yang, F. C., Negishi, A., Rheinstädter, M. C., Gillis, T. E., & Fudge, D. S. (2014). Self-assembly enhances the strength of fibers made from vimentin intermediate filament proteins. Biomacromolecules, 15(2), 574-581.
PDF Bernards, M. A., Oke, I., Heyland, A., & Fudge, D. S. (2014). Spontaneous unraveling of hagfish slime thread skeins is mediated by a seawater-soluble protein adhesive. The Journal of experimental biology, 217(8), 1263-1268.
PDF Fudge, D. S. (2014). Fifty years of JR Platt’s strong inference. The Journal of experimental biology, 217(8), 1202-1204.
PDF Herr, J. E., Clifford, A., Goss, G. G., & Fudge, D. S. (2014). Defensive slime formation in Pacific hagfish requires Ca2+ and aquaporin mediated swelling of released mucin vesicles. The Journal of experimental biology, 217: 2288-2296
PDF Gleason, J. E., Fudge, D. S., & Robinson, B. W. (2014). Eco-mechanics of lamellar autotomy in larval damselflies. The Journal of experimental biology, 217(2), 185-191.
PDF Negishi, A., Armstrong, C. L., Kreplak, L., Rheinstadter, M. C., Lim, L. T., Gillis, T. E., & Fudge, D. S. (2012). The production of fibers and films from solubilized hagfish slime thread proteins. Biomacromolecules, 13(11), 3475-3482.
PDF Greenberg, D. A., & Fudge, D. S. (2013). Regulation of hard α-keratin mechanics via control of intermediate filament hydration: matrix squeeze revisited. Proceedings of the Royal Society B: Biological Sciences, 280(1750), 20122158.
PDF Beriault, D. R., Haddad, O., McCuaig, J. V., Robinson, Z. J., Russell, D., Lane, E. B., & Fudge, D. S. (2012). The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes. PloS one, 7(2), e31320.
PDF Fudge, D. S., McCuaig, J. V., Van Stralen, S., Hess, J. F., Wang, H., Mathias, R. T., & FitzGerald, P. G. (2011). Intermediate filaments regulate tissue size and stiffness in the murine lens. Investigative ophthalmology & visual science, 52(6), 3860-3867.
PDF Ewoldt, R. H., Winegard, T. M., & Fudge, D. S. (2011). Non-linear viscoelasticity of hagfish slime. International Journal of Non-Linear Mechanics, 46(4), 627-636.
PDF Fudge, D. S., Hillis, S., Levy, N., & Gosline, J. M. (2010). Hagfish slime threads as a biomimetic model for high performance protein fibres. Bioinspiration & biomimetics, 5(3), 035002.
PDF Szewciw, L. J., De Kerckhove, D. G., Grime, G. W., & Fudge, D. S. (2010). Calcification provides mechanical reinforcement to whale baleen α-keratin. Proceedings of the Royal Society B: Biological Sciences, 277(1694), 2597-2605, rspb20100399.
PDF Herr, J. E., Winegard, T. M., O’Donnell, M. J., Yancey, P. H., & Fudge, D. S. (2010). Stabilization and swelling of hagfish slime mucin vesicles. The Journal of experimental biology, 213(7), 1092-1099.
PDF Winegard, T. M., & Fudge, D. S. (2010). Deployment of hagfish slime thread skeins requires the transmission of mixing forces via mucin strands. The Journal of Experimental Biology, 213(8), 1235-1240.
PDF LeBlanc, D. M., Wood, C. M., Fudge, D. S., & Wright, P. A. (2010). A fish out of water: gill and skin remodeling promotes osmo-and ionoregulation in the mangrove killifish Kryptolebias marmoratus. Physiological and Biochemical Zoology, 83(6), 932-949.
PDF Fudge, D.S., Winegard, T., Ewoldt, R.H. Beriault, D., Szewciw, L., and McKinley, G.H. (2009) From ultra-soft slime to hard alpha-keratins: the many lives of intermediate filaments. Integrative and Comparative Biology, 49(1), 32-39.
PDF Fudge, D. S., Szewciw, L. J., & Schwalb, A. N. (2009). Morphology and development of blue whale baleen: an annotated translation of Tycho Tullberg’s classic 1883 paper. Aquatic Mammals, 35(2), 226.
PDF Fudge, D., Russell, D., Beriault, D., Moore, W., Lane, E. B., & Vogl, A. W. (2008). The intermediate filament network in cultured human keratinocytes is remarkably extensible and resilient. PLoS One, 3(6), e2327.
PDF Kreplak, L., & Fudge, D. (2007). Biomechanical properties of intermediate filaments: from tissues to single filaments and back. Bioessays, 29(1), 26-35.
PDF Lim, J., Fudge, D. S., Levy, N., & Gosline, J. M. (2006). Hagfish slime ecomechanics: testing the gill-clogging hypothesis. Journal of experimental biology, 209(4), 702-710.
PDF John M. Gosline, Douglas S. Fudge, and Paul A. Guerette. (2006). Alpha-helical protein based materials and methods for making same (patent).
PDF Fudge, D. S., Levy, N., Chiu, S., & Gosline, J. M. (2005). Composition, morphology and mechanics of hagfish slime. Journal of experimental biology,208(24), 4613-4625.
PDF Fudge, D. S., & Gosline, J. M. (2004). Molecular design of the α–keratin composite: insights from a matrix–free model, hagfish slime threads. Proceedings of the Royal Society of London. Series B: Biological Sciences,271(1536), 291-299.
PDF Fudge, D. S., Gardner, K. H., Forsyth, V. T., Riekel, C., & Gosline, J. M. (2003). The mechanical properties of hydrated intermediate filaments: insights from hagfish slime threads. Biophysical Journal, 85(3), 2015-2027.