{"id":16,"date":"2021-06-30T12:34:36","date_gmt":"2021-06-30T19:34:36","guid":{"rendered":"https:\/\/sites.chapman.edu\/ibbalab\/?page_id=15"},"modified":"2021-06-30T12:34:36","modified_gmt":"2021-06-30T19:34:36","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.chapman.edu\/ibbalab\/publications\/","title":{"rendered":"PUBLICATIONS"},"content":{"rendered":"

SELECTED RECENT PUBLICATIONS<\/strong><\/p>\n

View the full list of publications by the Ibba Lab here: Google Scholar<\/a><\/em><\/p>\n

Steiner RE, Ibba M. (2019) Regulation of tRNA-dependent translational quality control.\u00a0IUBMB Life.\u00a0<\/em><\/p>\n

Steiner RE, Kyle AM, Ibba M (2019) Oxidation of phenylalanyl-tRNA synthetase positively regulates translational quality control.\u00a0PNAS<\/em>. 116, 10058-10063<\/p>\n

Tollerson II R, Witzky A, Ibba M (2018) Elongation factor P is required to maintain proteome homeostasis at high growth rate.\u00a0PNAS<\/em>. 115, 11072-11077.<\/p>\n

Sahai KS, Steiner RE, Au MG, Graham JM, Salamon N, Ibba M, Pierson TM (2018) FARS2 mutations presenting with pure spastic paraplegia and lesions of the dentate nuclei.\u00a0Ann Clin Transl Neurol.\u00a0<\/em>5, 1128-1133.<\/p>\n

Steiner RE, Ibba M (2018) Bridging the gap between tRNA modifications and the respiratory chain.\u00a0Biochem.\u00a0<\/em>57, 2565-2566.<\/p>\n

Witzky A, Hummels KR, Tollerson R II, Rajkovic A, Jones LA, Kearns DB, Ibba M (2018) EF-P post-translational modification has variable impact on polyproline translation in\u00a0Bacillus subtilis.\u00a0<\/em>mBio.\u00a0<\/em>9, e00306-18.<\/p>\n

Mohler K, Mann R, Kyle A, Reynolds N, Ibba M (2018) Aminoacyl-tRNA quality control is required for efficient activation of the TOR pathway regulator Gln3p.\u00a0RNA Biol<\/em>. 15, 594-603.<\/p>\n

Kelly P, Ibba M (2017) Aminoacyl-tRNA quality control provides a speedy solution to discriminate right from wrong.\u00a0J Mol Biol.\u00a0<\/em>5, 17-19.<\/p>\n

Tollerson R II, Witzky A, Ibba M (2017) Elongation factor P interactions with the ribosome are independent of pausing.\u00a0mBio<\/em>. 8, e01056-17.<\/p>\n

Hummels KR, Witzky A, Rajkovic A, Tollerson R 2nd, Jones LA, Ibba M, Kearns DB (2017) Carbonyl reduction by YmfI in Bacillus subtilis prevents accumulation of an inhibitory EF-P modification state.\u00a0Mol Microbiol<\/em>. 106, 236-251.<\/p>\n

Mohler K, Mann R, Bulwinkle TJ, Hopkins K, Hwang L, Reynolds NM, Gassaway B, Aerni HR, RinehartJ, Polymenis M, Faull K, Ibba M (2017) Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in\u00a0Saccharomyces cerevisiae.\u00a0<\/em>Nucelic Acids Res.\u00a0<\/em>45, 3985-3996.<\/p>\n

Mohler K, Aerni HR, Gassaway B, Ling J, Ibba M, Rinehart J (2017) MS-READ: Quantitative measurement of amino acid incorporation.\u00a0Biochim Biophys Acta.\u00a0<\/em>S0304-4165, 30033-8.<\/p>\n

Mohler K, Mann R, Ibba M (2017) Isoacceptor specific characterization of tRNA aminoacylation and misacylation\u00a0in vivo.\u00a0<\/em>Methods.\u00a0<\/em>113, 127-131.<\/p>\n

Elgamal S, Artsimovich I, Ibba M (2016) Maintenance of transcription-translation coupling \u00a0by elongation factor P.\u00a0mBio.\u00a0<\/em>7,\u00a0e01373-16.<\/p>\n

Moghal A, Hwang L, Faull K, Ibba M (2016) Multiple quality control pathways limit non-protein amino acid use by yeast cytoplasmic phenylalanyl-tRNA syntheses.\u00a0J. Biol. Chem.\u00a0<\/i>291, 15796-805.<\/p>\n

Katz A, Elgamal S, Rajkovic A, Ibba M (2016). Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology.\u00a0Mol. Microbiol.\u00a0<\/i>101, 545-58.<\/p>\n

Rajkovic A, Hummels KR, Witzky A, Erickson S, Gafken PR, Whitelegge JP, Faull KF,\u00a0Kearns DB, Ibba M (2016). Translation control of swarming proficiency in Bacillus subitlis by 5-Aminopentanolylated Elongation Factor P.\u00a0J. Biol. Chem.\u00a0<\/i>291, 10976-85.<\/p>\n

Bullwinkle T and Ibba M (2016) Translation quality control is critical for bacterial responses to amino acid stress.\u00a0Proc. Natl. Acad. Sci. USA.\u00a0<\/i>113, 2252-7.<\/p>\n

Rajkovic A, Erickson S, Witzky A, Branson OE, Seo J, Gafken PR, Frietas MA, Whitelegge JP, Faull KF, Navarre W, Darwin AJ and Ibba M. (2015) Cyclic rhamnosylated elongation factor P establishes antibiotic resistance in\u00a0Pseudomonas aeruginosa<\/i>.\u00a0mBio.\u00a0<\/i>6, e00823-15.<\/p>\n

Rajkovic A, Witzky A, Navarre W, Darwin AJ and Ibba M (2015) Elongation factor-P at the crossroads of the host-endosymbiont interface. \u00a0Microbial Cell.<\/i>\u00a02, 360-362.<\/p>\n

Shepherd J and Ibba M (2015) Bacterial transfer RNAs.\u00a0FEMS Microbiol Rev.<\/i>\u00a039, 280-300.<\/p>\n

Shepherd J and\u00a0Ibba M\u00a0(2015) Bacterial transfer RNAs.\u00a0FEMS Microbiol Rev.<\/em>\u00a039, 280-300.<\/p>\n

Ibba M.\u00a0(2015) Transfer RNA comes of age.\u00a0RNA<\/em>\u00a021, 648-649.<\/p>\n

Williams-Wagner RN, Grundy FJ, Raina M,\u00a0Ibba M\u00a0and Henkin TM (2015) The\u00a0Bacillus subtilis<\/em>tyrZ<\/em>\u00a0gene encodes a highly selective tyrosyl-tRNA synthetase and is regulated by a MarR regulator and T box riboswitch.\u00a0J. Bacteriol.<\/em>\u00a0197, 1624-1631.<\/p>\n

Elgamal S, Katz A, Hersch SJ, Newsom D, White P, Navarre WW and\u00a0Ibba, M.\u00a0(2014) EF-P dependent pauses integrate proximal and distal signals during translation.\u00a0PLoS Genetics<\/em>\u00a010\u00a0e1004553.PDF<\/a><\/p>\n

Bullwinkle TJ, Reynolds NM, Raina M, Moghal A, Matsa E, Rajkovic A., Kayadibi H, Fazlollahi F, Ryan C, Howitz N, Faull K, Lazazzera BA and\u00a0Ibba M.\u00a0(2014) Oxidation of cellular amino acid pools leads to cytotoxic mistranslation of the genetic code.\u00a0eLife\u00a0<\/em>e02501.PDF<\/a><\/p>\n

Bullwinkle TJ, Lazazzera BA and\u00a0Ibba M.\u00a0(2014) Quality control and infiltration of translation by amino acids outside of the genetic code.\u00a0Annu. Rev. Genet.<\/em>\u00a048,\u00a0149-166.\u00a0PDF<\/a><\/p>\n

Hersch SJ, Elgamal S, Katz A,\u00a0Ibba M\u00a0and Navarre WW (2014) Translation initiation rate determines the impact of ribosome stalling on bacterial protein synthesis.\u00a0J. Biol. Chem.<\/em>\u00a0289, 28160-28171.PDF<\/a><\/p>\n

Shepherd J and\u00a0Ibba M\u00a0(2014) Relaxed substrate specificity leads to extensive tRNA mischarging by Streptococcus pneumoniae class I and class II aminoacyl-tRNA synthetases.\u00a0mBio<\/em>\u00a05, e01656-14PDF<\/a><\/p>\n

Raina M and\u00a0Ibba M\u00a0(2014) tRNAs as regulators of biological processes.\u00a0Front. Genet.<\/em>\u00a05\u00a0171.PDF<\/a><\/p>\n

Raina M, Moghal A, Kano A, Jerums M, Schnier PD, Luo S, Deshpande R, Bondarenko PV, Lin H and\u00a0Ibba M.\u00a0(2014) Reduced amino acid specificity of mammalian tyrosyl-tRNA synthetase is associated with elevated mistranslation of Tyr codons.\u00a0J. Biol. Chem.\u00a0<\/em>289, 17780-17790.PDF<\/a><\/p>\n

Katz A, Solden L, Zou SB, Navarre WW and\u00a0Ibba M.\u00a0(2014) Molecular evolution of protein-RNA mimicry as a mechanism for translational control.\u00a0Nucleic Acids Res.<\/em>\u00a042, 3261-3271.PDF<\/a><\/p>\n

OTHER RELEVANT PUBLICATIONS<\/strong><\/p>\n

Bullwinkle TJ, Zou SB, Rajkovic A, Hersch SJ, Elgamal S, Robinson N, Smil D, Bolshan Y, Navarre WW and\u00a0Ibba M.\u00a0(2013) (R)-\u03b2-lysine modified elongation factor P functions in translation elongation.\u00a0J. Biol. Chem<\/em>\u00a0288, 4416-4423.PDF<\/a><\/p>\n

Yadavalli SS and\u00a0Ibba M.\u00a0(2013) Selection of tRNA charging quality control mechanisms that increase mistranslation of the genetic code.\u00a0Nucleic Acids Res.<\/em>\u00a041, 1104-1112.PDF<\/a><\/p>\n

Shepherd J and\u00a0Ibba M\u00a0(2013) Lipid II-independent trans editing of mischarged tRNAs by the penicillin resistance factor MurM.\u00a0J. Biol. Chem.<\/em>\u00a0288, 25915-25923.PDF<\/a><\/p>\n

Elo, JM, Yadavalli SS, Euro L, Isohanni P, G\u00f6tz A, Carroll C, Valanne L, Alkuraya FS, Uusimaa J, Paetau A, Caruso EM, Pihko H,\u00a0Ibba M,\u00a0Tyynismaa H & Suomalainen A (2012) Mitochondrial phenylalanyl-tRNA synthetase mutations underlie fatal infantile Alpers encephalopathy.\u00a0Hum. Mol. Genet.<\/em>\u00a021, 4521-4529.<\/p>\n

Roy H, Zou SB, Bullwinkle TJ, Wolfe BS, Gilreath MS, Forsyth CJ, Navarre WW &\u00a0Ibba M\u00a0(2011) The tRNA synthetase paralog PoxA modifies elongation factor-P with (R<\/em>)-\u03b2-lysine.\u00a0Nat. Chem. Biol.<\/em>\u00a07, 667-669.\u00a0Nature Research Highlight<\/a>.\u00a0OSU news<\/a>.<\/p>\n

Reynolds NM, Lazazzera BA &\u00a0Ibba M.\u00a0(2010) Cellular mechanisms that control mistranslation.\u00a0Nat Rev Microbiol\u00a0<\/em>8,\u00a0<\/em>849-856.<\/p>\n

Weygand-Durasevic I &\u00a0Ibba M.\u00a0(2010) New roles for codon usage.\u00a0Science\u00a0<\/em>329,\u00a01473-1474.<\/em><\/p>\n

Roy H &\u00a0Ibba M.\u00a0(2010) Bridging the gap between ribosomal and non-ribosomal protein synthesis.\u00a0Proc Natl Acad Sci USA\u00a0<\/em>107,\u00a0<\/em>14517-14518.<\/em><\/p>\n

Navarre WW, Zou S, Roy H, Xie JL, Savchenko A, Singer A, Evdokimova E, Prost LR, Kumar R,\u00a0Ibba M\u00a0& Fang FC. (2010) PoxA, YjeK and elongation factor P coordinately modulate virulence and drug resistance in\u00a0Salmonella enterica. Mol Cell\u00a0<\/em>39,\u00a0209-221.<\/p>\n

Reynolds NM, Ling J, Roy H, Banerjee R, Repasky SE, Hamel P &\u00a0Ibba M. (2010) Cell-specific differences in the requirements for translational quality control.\u00a0Proc Natl Acad Sci USA\u00a0<\/em>107, 4063-4068..<\/p>\n

Ling J, So BR, Yadavalli SS, Roy H, Shoji S, Fredrick K, Musier-Forsyth K &\u00a0Ibba M. (2009) Resampling and editing of mischarged tRNA prior to translation elongation.\u00a0Mol Cell<\/em>\u00a033, 654-660.<\/p>\n

Roy H &\u00a0Ibba M.\u00a0(2008) RNA-dependent lipid remodeling by bacterial multiple peptide resistance factors.\u00a0Proc Natl Acad Sci USA<\/em>\u00a0105, 4667-4672.<\/p>\n

Ling J, Roy H, Qin D, Rubio MA, Alfonzo JD, Fredrick K &\u00a0Ibba M. (2007) Pathogenic mechanism of a human mitochondrial tRNAPhe<\/sup>\u00a0mutation associated with MERRF syndrome.\u00a0Proc Natl Acad Sci USA<\/em>\u00a0104, 15299-15304.<\/p>\n

Ling J, Roy H &\u00a0Ibba M. (2007) Mechanism of tRNA-dependent editing in translational quality control.\u00a0Proc Natl Acad Sci USA<\/em>\u00a0104, 72-77.<\/p>\n

Sauerwald A, Zhu W, Major TA, Roy H, Palioura S, Jahn D, Whitman W, Yates JR 3rd,\u00a0Ibba M\u00a0& S\u00f6ll D. (2005) RNA-dependent cysteine biosynthesis in archaea.\u00a0Science<\/em>\u00a0307, 1969-1972.<\/p>\n

Roy H, Ling J, Irnov and\u00a0Ibba M. (2004) Post-transfer editing\u00a0in vitro<\/em>\u00a0and\u00a0in vivo<\/em>\u00a0by the beta-subunit of phenylalanyl-tRNA synthetase.\u00a0EMBO J.<\/em>\u00a023, 4639-4648.<\/p>\n

Jester B, Levengood J, Roy H,\u00a0Ibba M\u00a0& Devine K. (2003) Non-orthologous replacement of lysyl-tRNA synthetase prevents addition of lysine analogs to the genetic code.\u00a0Proc Natl Acad Sci USA<\/em>\u00a0100, 14351-14356.<\/p>\n","protected":false},"excerpt":{"rendered":"

SELECTED RECENT PUBLICATIONS View the full list of publications by the Ibba Lab here: Google Scholar Steiner RE, Ibba M. (2019) Regulation of tRNA-dependent translational quality control.\u00a0IUBMB Life.\u00a0 Steiner RE, Kyle AM, Ibba M (2019) Oxidation of phenylalanyl-tRNA synthetase positively regulates translational quality control.\u00a0PNAS. 116, 10058-10063 Tollerson II R, Witzky A, Ibba M (2018) Elongation… Continue Reading PUBLICATIONS<\/a><\/p>\n","protected":false},"author":62,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-16","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/pages\/16","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/users\/62"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/comments?post=16"}],"version-history":[{"count":0,"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/pages\/16\/revisions"}],"wp:attachment":[{"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/media?parent=16"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.chapman.edu\/ibbalab\/wp-json\/wp\/v2\/tags?post=16"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}